Description

3-(3-Methoxy-Benzoyl)-1H-Indole-5-Carbonitrile CAS NO 478677-80-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-based molecular structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic molecules.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex indole-containing compounds for various high-value applications.
• Biochemical Research: May serve as a precursor or reference standard in biochemical assays and pharmacological studies.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	3-(3-Methoxy-Benzoyl)-1H-Indole-5-Carbonitrile
CAS No.	478677-80-4
Molecular Formula	C17H12N2O2
Molecular Weight	276.29 g/mol
Synonyms	5-Cyano-3-(3-methoxybenzoyl)indole; 1H-Indole-5-carbonitrile, 3-(3-methoxybenzoyl)-; 3-(3-Methoxybenzoyl)-1H-indole-5-carbonitrile; 3-(3-Methoxybenzoyl)indole-5-carbonitrile; 3-(m-Methoxybenzoyl)-1H-indole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-(3-Methoxy-Benzoyl)-1H-Indole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.