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tert-Butyl 2-Amino-7-Oxo-6,7-Dihydrothiazolo[4,5-C]Pyridine-5(4H)-Carboxylate CAS NO 478624-69-0


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CAS No.:478624-69-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 2-Amino-7-Oxo-6,7-Dihydrothiazolo[4,5-C]Pyridine-5(4H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those with thiazolo[4,5-c]pyridine scaffolds.
  • Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for discovering new bioactive molecules.
  • API Development: Serves as a critical precursor in the multi-step synthesis of potential therapeutic agents, including kinase inhibitors.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
  • Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item Detail
Product Name tert-Butyl 2-Amino-7-Oxo-6,7-Dihydrothiazolo[4,5-C]Pyridine-5(4H)-Carboxylate
CAS No. 478624-69-0
Molecular Formula C11H15N3O3S
Molecular Weight 269.32 g/mol
Synonyms 5-[(tert-Butoxy)carbonyl]-2-amino-4,7-dihydrothiazolo[4,5-c]pyridin-7-one; 2-Amino-7-oxo-4,5,6,7-tetrahydrothiazolo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 2-amino-7-oxo-4,5,6,7-tetrahydrothiazolo[4,5-c]pyridine-5-carboxylate; BOC-protected thiazolopyridinone intermediate; 478624-69-0; Thiazolo[4,5-c]pyridine-5-carboxylate derivative
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Quality Control

Our tert-Butyl 2-Amino-7-Oxo-6,7-Dihydrothiazolo[4,5-C]Pyridine-5(4H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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