Description

D-[2-2H]Glyceraldehyde is a stable isotope-labeled analog of glyceraldehyde, specifically deuterated at the 2-position. This compound is essential for advanced research in metabolic pathway analysis and enzyme kinetics, providing a non-radioactive tracer for precise mechanistic studies. It is a critical reagent for scientists in pharmaceutical development, biochemistry, and analytical chemistry who require high-purity, isotopically defined materials for mass spectrometry and NMR spectroscopy.

Application

• Metabolic Tracer Studies: Used in Stable Isotope-Resolved Metabolomics (SIRM) to track carbon flux through central metabolic pathways like glycolysis and the pentose phosphate pathway.
• Enzyme Mechanism Investigation: Serves as a deuterated substrate for studying the stereochemistry and kinetics of aldolases, isomerases, and dehydrogenases.
• Biochemical Research: A key intermediate in the synthesis of deuterated sugars and other labeled biomolecules for structural and functional studies.
• Pharmaceutical Development: Employed in the research and development of metabolic-targeted therapies and diagnostic agents.
• Analytical Standard: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Nuclear Magnetic Resonance (NMR) for accurate quantification of glyceraldehyde in complex biological matrices.
• Nutritional Science Research: Applied in studies investigating carbohydrate metabolism and energy homeostasis.

Basic Information

Product Name	D-[2-2H]Glyceraldehyde
CAS No.	478529-64-5
Molecular Formula	C3H5D1O3
Molecular Weight	91.08 g/mol (for monoisotopic mass)
Synonyms	(2R)-2-Deuterio-2,3-dihydroxypropanal; D-Glyceraldehyde-2-d; (R)-Glyceraldehyde-2-d; 2-Deuterio-D-glyceraldehyde; [2-2H]-D-Glyceraldehyde; Deuterated D-glyceraldehyde; D-Glyceraldehyde (2-2H); Stable Isotope Labeled Glyceraldehyde
EINECS	Contact for details

Quality Control

Every batch of our D-[2-2H]Glyceraldehyde is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR and Mass Spectrometry. Certificates of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles are provided to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or syrup
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.