Description

D-[3,3'-2H2]Glyceraldehyde is a stable isotope-labeled analog of the fundamental triose sugar, glyceraldehyde, specifically deuterated at the 3 and 3' positions. This compound is a critical tool for advanced research, enabling precise metabolic pathway tracing and structural elucidation through techniques like NMR spectroscopy and mass spectrometry. It is essential for scientists and manufacturers in pharmaceutical development, biochemical research, and analytical chemistry who require high-purity, isotopically defined building blocks for their studies and processes.

Application

• Metabolic Pathway Tracing: Used as a deuterium-labeled tracer in in vitro and in vivo studies to investigate glycolysis, gluconeogenesis, and the pentose phosphate pathway.
• NMR Spectroscopy Internal Standard: Serves as a crucial internal reference or shift standard in nuclear magnetic resonance (NMR) analysis due to its defined deuterium substitution.
• Mass Spectrometry (MS) Applications: Employed as a stable isotope-labeled internal standard for the accurate quantification of glyceraldehyde and related metabolites in complex biological matrices via LC-MS or GC-MS.
• Biochemical Research Reagent: Acts as a key substrate or intermediate in enzymatic studies, particularly those involving aldolases, kinases, and isomerases.
• Pharmaceutical Research: Utilized in the synthesis and development of labeled drug candidates and metabolites for pharmacokinetic and pharmacodynamic studies.
• Chemical Synthesis Building Block: Provides a deuterated starting material for the synthesis of more complex, labeled carbohydrates and organic molecules.

Basic Information

Product Name	D-[3,3'-2H2]Glyceraldehyde
CAS No.	478529-58-7
Molecular Formula	C3H4D2O3
Molecular Weight	92.09 g/mol
Synonyms	(2R)-2,3-Dihydroxy-1,1,3,3-tetradeuteriopropanal; D-Glyceraldehyde-3,3-d2; (R)-Glyceraldehyde-3,3-d2; Deuterated D-Glyceraldehyde; [3,3'-2H2]-D-Glyceraldehyde; D-Glyceraldehyde-d2; (R)-2,3-Dihydroxypropanal-3,3-d2; Stable Isotope Labeled Glyceraldehyde
EINECS	Contact for details

Quality Control

Every batch of our D-[3,3'-2H2]Glyceraldehyde is produced and analyzed under strict quality management protocols to ensure the highest standards of isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % D), chemical purity by HPLC, and specific optical rotation. Our quality systems are designed to meet the rigorous demands of research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to Off-White Solid
Identification (IR)	Conforms to Structure
Identification (NMR)	Conforms to Structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.