Description

Dl-[1,2,3-13C3]Glyceraldehyde is a stable isotope-labeled analog of glyceraldehyde, a fundamental three-carbon sugar and a key intermediate in carbohydrate metabolism. This compound is specifically enriched with carbon-13 at the 1, 2, and 3 positions, making it an indispensable tool for advanced metabolic research and analytical method development. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors who require precise isotopic tracers for mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy studies.

Application

• Metabolic Pathway Tracing: As a 13C-labeled precursor for studying glycolysis, the pentose phosphate pathway, and other central carbon metabolic fluxes in cell cultures and biological systems.
• Internal Standard for Quantitative Analysis: Used in LC-MS and GC-MS workflows as a stable isotope-labeled internal standard (SIL-IS) for the accurate quantification of endogenous glyceraldehyde and related metabolites.
• NMR Spectroscopy Studies: Enables detailed structural and dynamic analysis of biochemical reactions and enzyme mechanisms due to its distinct 13C NMR signature.
• Biochemical Research: Serves as a critical reagent in enzymatic studies, particularly for aldolases and kinases involved in sugar metabolism.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the incorporation of sugar moieties into drug molecules or their metabolites.
• Diagnostic Assay Development: Used in the calibration and validation of clinical diagnostic assays that measure sugars or metabolic disorders.

Basic Information

Product Name	Dl-[1,2,3-13C3]Glyceraldehyde
CAS No.	478529-56-5
Molecular Formula	C313C3H6O3
Molecular Weight	95.06 g/mol (for 13C3 labeled form)
Synonyms	DL-Glyceraldehyde-1,2,3-13C3; (RS)-Glyceraldehyde-1,2,3-13C3; 2,3-Dihydroxypropanal-1,2,3-13C3; 1,2,3-13C3-Glyceraldehyde; Glyceraldehyde-13C3; [13C3]-Glyceraldehyde; Isotopically labeled glyceraldehyde; 13C Labeled triose sugar
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Dl-[1,2,3-13C3]Glyceraldehyde is characterized to confirm isotopic enrichment, chemical purity, and identity. Certificates of Analysis (COA) are available upon request and provide detailed results for parameters including isotopic purity (Atom % 13C), chemical purity by HPLC, and specific identification tests.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Purity (Atom % 13C)	≥ 99% at each labeled position (1,2,3)
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.