Description

D-[2-13C]Threose is a stable isotope-labeled derivative of the monosaccharide threose, specifically enriched with carbon-13 at the 2-position. This compound is a critical tool for advanced metabolic and biochemical research, enabling precise tracing of carbohydrate pathways and structural elucidation via Nuclear Magnetic Resonance (NMR) spectroscopy. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in isotope-based studies, metabolic flux analysis, and the synthesis of labeled complex carbohydrates.

Application

• NMR Spectroscopy & Structural Analysis: Serves as an internal standard and tracer for elucidating molecular structures and dynamics in carbohydrate chemistry.
• Metabolic Pathway Tracing (Metabolic Flux Analysis): Used to track and quantify the flow of carbon in biological systems, providing insights into cellular metabolism.
• Isotope-Labeled Intermediate Synthesis: Acts as a key building block for the synthesis of more complex 13C-labeled sugars, nucleotides, or glycoconjugates.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace the fate of sugar-containing drug molecules.
• Biochemical Research: Facilitates studies on enzyme mechanisms, carbohydrate metabolism, and glycosylation processes.
• Analytical Reference Standard: Used as a high-purity calibrant in mass spectrometry (MS) and chromatography methods for accurate quantification.

Basic Information

Product Name	D-[2-13C]Threose
CAS No.	478506-49-9
Molecular Formula	C4H8O4 (with 13C at position 2)
Molecular Weight	~122.11 g/mol (13C enriched)
Synonyms	(2-13C)-D-Threose; D-Threose-2-13C; 13C Labeled D-Threose; Isotopic D-Threose; [2-13C]-D-Threofuranose; Stable Isotope-Labeled Threose; 13C Enriched Aldotetrose; Four-carbon sugar-2-13C
EINECS	Contact for details

Quality Control

Our D-[2-13C]Threose is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity, essential for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and specific optical rotation. We adhere to relevant industry standards for fine chemicals and stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.