Description

Gabapentin Enacarbil is a prodrug of the anticonvulsant and analgesic gabapentin, specifically designed for enhanced oral bioavailability and sustained release. This compound is critical for pharmaceutical development, offering a more predictable pharmacokinetic profile compared to its parent molecule. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development of advanced neurological and pain management therapeutics.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of extended-release oral tablets for neurological conditions.
• Key intermediate in advanced pharmaceutical research for neuropathic pain management.
• Development of treatments for postherpetic neuralgia and restless legs syndrome (RLS).
• Reference standard in analytical laboratories for quality control and method validation.
• Pre-clinical and clinical research material for pharmacokinetic and pharmacodynamic studies.
• Manufacturing of generic and branded pharmaceutical products requiring a prodrug form of gabapentin.

Basic Information

Product Name	Gabapentin Enacarbil
CAS No.	478296-72-9
Molecular Formula	C16H25NO4
Molecular Weight	295.37 g/mol
Synonyms	XP13512; (1-{[({(1RS)-1-[({(2-Methylpropanoyl)oxy}methoxy)carbonyl]cyclohexyl}methyl)amino]methyl}cyclohexyl)acetic acid; Gabapentin Enacarbil Extended-Release; Gabapentin Enacarbil ER; Gabapentin Prodrug; Horizant (Brand Name)
EINECS	Contact for details

Quality Control

Our Gabapentin Enacarbil is manufactured under strict quality systems and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material compliant with current Good Manufacturing Practice (cGMP) standards for advanced pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.