Description

Pentanoic Acid, 4-Amino-5-[[2-(1H-Indol-3-Yl)Ethyl]Amino]-5-Oxo-, (4S)- is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This molecule serves as a critical chiral building block or intermediate for the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and specialized fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Bioconjugation Chemistry: Serves as a specialized linker or functional handle for attaching payloads in antibody-drug conjugate (ADC) and prodrug development.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Asymmetric Synthesis: Acts as a starting material or intermediate in stereoselective catalytic reactions to construct complex molecular architectures.
• High-Value Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	Pentanoic Acid, 4-Amino-5-[[2-(1H-Indol-3-Yl)Ethyl]Amino]-5-Oxo-, (4S)-
CAS No.	478273-36-8
Molecular Formula	C₁₅H₁₉N₃O₃
Molecular Weight	289.33 g/mol
Synonyms	(4S)-4-Amino-5-[[2-(1H-Indol-3-yl)ethyl]amino]-5-oxopentanoic acid; (S)-4-Amino-5-(2-(1H-indol-3-yl)ethylamino)-5-oxopentanoic acid; L-Glutamine, N-[2-(1H-indol-3-yl)ethyl]-; N-[2-(1H-Indol-3-yl)ethyl]-L-glutamine; Tryptophanylglutamine; WE-1; A tryptophan-glutamine dipeptide analog
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 4-Amino-5-[[2-(1H-Indol-3-Yl)Ethyl]Amino]-5-Oxo-, (4S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.