Description

3-Chlorophenyl (E)-3-(6-Bromo-1,3-Benzodioxol-5-Yl)-2-Propenoate is a high-purity, synthetic organic compound characterized by its unique halogenated benzodioxole and propenoate ester structure. This compound serves as a critical advanced intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific molecular architecture enables targeted biological activity. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides, leveraging its halogenated benzodioxole moiety.
• Chemical Biology Probe: Serves as a scaffold or precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Potential monomer or precursor for specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Utilized in university and CRO settings for methodological development and exploratory synthetic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of complex, bespoke molecules for client-specific applications.

Basic Information

Product Name	3-Chlorophenyl (E)-3-(6-Bromo-1,3-Benzodioxol-5-Yl)-2-Propenoate
CAS No.	478259-32-4
Molecular Formula	C16H10BrClO4
Molecular Weight	381.61 g/mol
Synonyms	(E)-3-(6-Bromo-1,3-benzodioxol-5-yl)-2-propenoic acid 3-chlorophenyl ester; 3-Chlorophenyl 3-(6-Bromo-1,3-benzodioxol-5-yl)acrylate; 6-Bromo-1,3-benzodioxole-5-acrylic acid 3-chlorophenyl ester; (E)-3-(6-Bromo-benzo[1,3]dioxol-5-yl)-acrylic acid 3-chloro-phenyl ester; 3-Chlorophenyl (E)-3-(6-bromo-1,3-benzodioxol-5-yl)acrylate; 478259-32-4; Propenoic acid, 3-(6-bromo-1,3-benzodioxol-5-yl)-, 3-chlorophenyl ester, (E)-
EINECS	Contact for details

Quality Control

Our 3-Chlorophenyl (E)-3-(6-Bromo-1,3-Benzodioxol-5-Yl)-2-Propenoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC/MS for solvent residue analysis, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.