Description

4-Amino-5-Benzoyl-2-[(3-Fluorobenzyl)Sulfanyl]-3-Thiophenecarbonitrile is a high-value, multi-functional heterocyclic building block with a complex molecular architecture. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique thiophene core and functional groups enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapeutic programs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its bio-active scaffold.
• Material Science Research: Serves as a building block for advanced organic electronic materials, such as organic semiconductors and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Amino-5-Benzoyl-2-[(3-Fluorobenzyl)Sulfanyl]-3-Thiophenecarbonitrile
CAS No.	478081-56-0
Molecular Formula	C19H13FN2OS2
Molecular Weight	368.45 g/mol
Synonyms	4-Amino-5-benzoyl-2-[(3-fluorophenyl)methyl]sulfanyl-3-thiophenecarbonitrile; 2-[(3-Fluorobenzyl)thio]-4-amino-5-benzoyl-3-thiophenecarbonitrile; 4-Amino-2-((3-fluorobenzyl)thio)-5-benzoylthiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 4-amino-5-benzoyl-2-[(3-fluorophenyl)methyl]thio]-; 478081-56-0; AKOS005258065; CTK8G0117; ZINC000103074777
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Benzoyl-2-[(3-Fluorobenzyl)Sulfanyl]-3-Thiophenecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.