Description

3-Ethyl-5-[(Z)-(4-Hydroxyphenyl)Methylidene]-2-(4H-1,2,4-Triazol-4-Ylimino)-1,3-Thiazolan-4-One is a sophisticated heterocyclic compound that serves as a key intermediate in advanced organic synthesis. Its unique molecular architecture, featuring fused thiazolone and triazole rings, makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. This high-purity chemical is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical companies focused on creating next-generation products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways where the triazole and thiazolone motifs are pharmacologically active.
• Agrochemical Research: Used in the development of new fungicides and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, or advanced polymers requiring specific light-absorbing or charge-transport properties.
• Chemical Biology Probe: Utilized in research to study protein-ligand interactions or enzyme inhibition due to its potential metal-chelating and hydrogen-bonding capabilities.
• Dye and Pigment Intermediate: The conjugated system and hydroxyphenyl group make it a candidate for synthesizing specialized dyes and colorants.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including cyclization and condensation reactions.

Basic Information

Product Name	3-Ethyl-5-[(Z)-(4-Hydroxyphenyl)Methylidene]-2-(4H-1,2,4-Triazol-4-Ylimino)-1,3-Thiazolan-4-One
CAS No.	478078-11-4
Molecular Formula	C₁₄H₁₃N₅O₂S
Molecular Weight	315.35 g/mol
Synonyms	4H-1,2,4-Triazol-4-amine, 3-ethyl-5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]-2-thioxo-2,3-dihydro- (9CI); 3-Ethyl-5-[(Z)-2-(4-hydroxyphenyl)vinyl]-2-thioxo-2,3-dihydro-4H-1,2,4-triazol-4-amine; 3-Ethyl-5-[(Z)-(4-hydroxyphenyl)methylene]-2-(4H-1,2,4-triazol-4-ylimino)-1,3-thiazolidin-4-one; CAS 478078-11-4
EINECS	Contact for details

Quality Control

Every batch of 3-Ethyl-5-[(Z)-(4-Hydroxyphenyl)Methylidene]-2-(4H-1,2,4-Triazol-4-Ylimino)-1,3-Thiazolan-4-One is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.