Description

3-[2-(2,5-Dimethyl-1H-Pyrrol-1-Yl)-3-Thienyl]-3-Oxopropanenitrile is a specialized heterocyclic building block featuring a unique pyrrole-thiophene core functionalized with a cyanoacetyl group. This compound matters as a high-value synthetic intermediate, enabling the construction of complex molecular architectures for advanced materials and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of new active ingredients for crop protection with potential novel modes of action.
• Organic Semiconductor Precursor: Serves as a precursor for π-conjugated molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Coordination Chemistry Ligand: The pyrrole and thiophene moieties can act as donors for metal complexation, useful in catalysis and sensor development.
• Dye and Pigment Synthesis: Employed in the creation of specialized heterocyclic dyes with specific optical properties.
• Academic & Contract Research: A valuable tool for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	3-[2-(2,5-Dimethyl-1H-Pyrrol-1-Yl)-3-Thienyl]-3-Oxopropanenitrile
CAS No.	478078-01-2
Molecular Formula	C15H14N2OS
Molecular Weight	270.35 g/mol
Synonyms	3-Oxo-3-[2-(2,5-dimethylpyrrol-1-yl)-3-thienyl]propanenitrile; 2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-(2-cyanoacetyl)thiophene; 3-[2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-thienyl]-3-oxopropanenitrile; 2-Cyano-1-[2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-thienyl]ethanone; (2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)(oxo)acetonitrile
EINECS	Contact for details

Quality Control

Our 3-[2-(2,5-Dimethyl-1H-Pyrrol-1-Yl)-3-Thienyl]-3-Oxopropanenitrile is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), our technical team is available to discuss tailored quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.