Description

2-(3-(Trifluoromethyl)Benzyl)Thiazole-4-Carboxylic Acid is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and bioavailability. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to accelerate the discovery and scalable production of next-generation therapeutics and crop protection agents.

Application

• As a critical pharmaceutical intermediate in the synthesis of drug candidates targeting various disease pathways.
• Utilized in agrochemical research for the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Serves as a specialized building block in medicinal chemistry for constructing complex molecules with tailored properties.
• Used in material science research for creating novel fluorinated polymers or liquid crystals.
• Acts as a precursor for ligand synthesis in catalysis and coordination chemistry.
• Employed in academic and industrial R&D for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-(3-(Trifluoromethyl)Benzyl)Thiazole-4-Carboxylic Acid
CAS No.	478030-66-9
Molecular Formula	C12H8F3NO2S
Molecular Weight	287.26 g/mol
Synonyms	2-[(3-Trifluoromethyl)benzyl]-1,3-thiazole-4-carboxylic acid; 2-[(3-Trifluoromethyl)phenyl]methyl]-4-thiazolecarboxylic acid; 4-Thiazolecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]methyl]-; 2-(3-(Trifluoromethyl)benzyl)thiazole-4-carboxylic acid; 2-[(3-Trifluoromethyl)benzyl]thiazole-4-carboxylic acid; α-(3-Trifluoromethylbenzyl)thiazole-4-carboxylic acid; 478030-66-9
EINECS	Contact for details

Quality Control

Our 2-(3-(Trifluoromethyl)Benzyl)Thiazole-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.