Description

5-tert-Butyl-Thiophene-2-Carboxylic Acid is a high-purity, functionalized heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for functional monomers or ligands in the creation of advanced polymers, conductive materials, or metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and the exploration of new heterocyclic chemistry.
• Ligand and Catalyst Preparation: The carboxylic acid group allows for derivatization into amides or esters, useful for creating specialized ligands for catalytic systems.

Basic Information

Product Name	5-tert-Butyl-Thiophene-2-Carboxylic Acid
CAS No.	478022-18-3
Molecular Formula	C9H12O2S
Molecular Weight	184.26 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-(1,1-dimethylethyl)-; 5-tert-Butyl-2-thiophenecarboxylic acid; 5-(tert-Butyl)thiophene-2-carboxylic acid; 5-tert-Butylthiophene-2-carboxylic acid; 2-Carboxy-5-tert-butylthiophene; 5-tert-Butyl-thiophene-2-carboxylate (acid); 5-(1,1-Dimethylethyl)-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.