Description

5-[2-(3-Chloro-1-Benzothiophen-2-Yl)Vinyl]-3-Methyl-4-Nitroisoxazole is a high-value, synthetically complex heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring fused benzothiophene and isoxazole rings with nitro and vinyl substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its bioactive nitroisoxazole moiety.
• Material Science: Serves as a building block for organic semiconductors, nonlinear optical (NLO) materials, and other advanced functional materials due to its conjugated π-system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in organic chemistry and heterocyclic compound synthesis.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments where the benzothiophene core contributes to color and stability.

Basic Information

Product Name	5-[2-(3-Chloro-1-Benzothiophen-2-Yl)Vinyl]-3-Methyl-4-Nitroisoxazole
CAS No.	477868-37-4
Molecular Formula	C₁₄H₉ClN₂O₃S
Molecular Weight	320.75 g/mol
Synonyms	3-Methyl-5-[(E)-2-(3-chlorobenzo[b]thiophen-2-yl)ethenyl]-4-nitroisoxazole; 5-[(E)-2-(3-Chloro-1-benzothiophen-2-yl)vinyl]-3-methyl-4-nitro-1,2-oxazole; 3-Methyl-4-nitro-5-[2-(3-chlorobenzo[b]thien-2-yl)vinyl]isoxazole; 5-(2-(3-Chlorobenzo[b]thiophen-2-yl)vinyl)-3-methyl-4-nitroisoxazole; (E)-5-(2-(3-Chlorobenzo[b]thiophen-2-yl)vinyl)-3-methyl-4-nitroisoxazole
EINECS	Contact for details

Quality Control

Our 5-[2-(3-Chloro-1-Benzothiophen-2-Yl)Vinyl]-3-Methyl-4-Nitroisoxazole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.