Description

Ethyl 2-(4-Methoxyphenyl)-1-indolizinecarboxylate is a high-purity, synthetically valuable indolizine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and photochromic materials.
• Academic & Contract Research: Essential for methodological studies in heterocyclic chemistry, including cyclization and cross-coupling reactions.
• Fluorescent Probe Synthesis: The indolizine core is utilized to construct fluorescent dyes and molecular sensors for biological imaging and detection.

Basic Information

Product Name	Ethyl 2-(4-Methoxyphenyl)-1-indolizinecarboxylate
CAS No.	477862-79-6
Molecular Formula	C18H17NO3
Molecular Weight	295.33 g/mol
Synonyms	Ethyl 2-(4-methoxyphenyl)indolizine-1-carboxylate; 1H-Indolizine-1-carboxylic acid, 2-(4-methoxyphenyl)-, ethyl ester; 2-(4-Methoxyphenyl)-1-indolizinecarboxylic Acid Ethyl Ester; Ethyl 2-p-anisylindolizine-1-carboxylate; 1-Carbethoxy-2-(4-methoxyphenyl)indolizine; 477862-79-6; AI3-32862
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-(4-Methoxyphenyl)-1-indolizinecarboxylate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure lot-to-lot consistency and compliance with your research or production specifications. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.