Description

(5-Methyl-1,3,4-Oxadiazol-2-Yl)Methyl 1-[(4-Methylphenyl)Sulfonyl]-1H-Indol-4-Yl Ether is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on oncology, neurology, and anti-inflammatory drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel small-molecule drug candidates, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Development: Used in the pilot-scale and commercial-scale production of target APIs requiring its specific indole-oxadiazole hybrid structure.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor modulation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(5-Methyl-1,3,4-Oxadiazol-2-Yl)Methyl 1-[(4-Methylphenyl)Sulfonyl]-1H-Indol-4-Yl Ether
CAS No.	477856-99-8
Molecular Formula	C20H19N3O4S
Molecular Weight	397.45 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-4-[[(5-methyl-1,3,4-oxadiazol-2-yl)methoxy]methyl]-1H-indole; 4-[[(5-Methyl-1,3,4-oxadiazol-2-yl)methoxy]methyl]-1-(4-methylphenyl)sulfonylindole; (5-Methyl-1,3,4-oxadiazol-2-yl)methyl 1-(p-tolylsulfonyl)indol-4-yl ether; 1-Tosyl-4-((5-methyl-1,3,4-oxadiazol-2-yl)methoxymethyl)indole; 477856-99-8; Indole-4-yl ether derivative; Tosyl-indole-oxadiazole hybrid
EINECS	Contact for details

Quality Control

Our (5-Methyl-1,3,4-Oxadiazol-2-Yl)Methyl 1-[(4-Methylphenyl)Sulfonyl]-1H-Indol-4-Yl Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.