Description

Methyl 1-[5-(3-Bromo-2-Thienyl)-3-Cyano-1H-Pyrrol-2-Yl]-4-Piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Heterocyclic Compound Synthesis: Serves as a specialized building block for constructing complex molecules containing pyrrole, piperidine, and thiophene rings.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and development of proprietary chemical entities for clinical trials.
• Academic Research: Employed in university and institutional labs for studying novel organic reactions and synthesizing biologically active molecules.

Basic Information

Product Name	Methyl 1-[5-(3-Bromo-2-Thienyl)-3-Cyano-1H-Pyrrol-2-Yl]-4-Piperidinecarboxylate
CAS No.	477854-09-4
Molecular Formula	C16H16BrN3O2S
Molecular Weight	394.29 g/mol
Synonyms	Methyl 4-(5-(3-bromothiophen-2-yl)-3-cyano-1H-pyrrol-2-yl)piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-[5-(3-bromo-2-thienyl)-3-cyano-1H-pyrrol-2-yl]-, methyl ester; 477854-09-4; Methyl 4-(5-(3-bromothiophen-2-yl)-3-cyano-1H-pyrrol-2-yl)piperidine-1-carboxylate; CAS 477854-09-4
EINECS	Contact for details

Quality Control

Our Methyl 1-[5-(3-Bromo-2-Thienyl)-3-Cyano-1H-Pyrrol-2-Yl]-4-Piperidinecarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.