Description

1-Oxo-2-(3-Pyridinylmethyl)-1,2-Dihydro-4-Isoquinolinecarboxylic Acid CAS NO 477851-07-3 is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is integral to the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the synthesis of complex organic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the synthesis of complex heterocyclic compounds, leveraging its isoquinoline and pyridine motifs.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays and proteomics research.
• Agrochemical Development: May serve as an intermediate in the synthesis of novel crop protection agents and pesticides.

Basic Information

Product Name	1-Oxo-2-(3-Pyridinylmethyl)-1,2-Dihydro-4-Isoquinolinecarboxylic Acid
CAS No.	477851-07-3
Molecular Formula	C₁₇H₁₂N₂O₃
Molecular Weight	292.29 g/mol
Synonyms	4-Isoquinolinecarboxylic acid, 1,2-dihydro-1-oxo-2-(3-pyridinylmethyl)-; 2-(Pyridin-3-ylmethyl)-1,2-dihydro-1-oxo-4-isoquinolinecarboxylic acid; 1,2-Dihydro-1-oxo-2-(3-pyridinylmethyl)-4-isoquinolinecarboxylic acid; 1-Oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxylic acid; 477851-07-3; UNII-9Q5U1Y1B5F; 9Q5U1Y1B5F
EINECS	Contact for details

Quality Control

Our 1-Oxo-2-(3-Pyridinylmethyl)-1,2-Dihydro-4-Isoquinolinecarboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.