Description

2-((1-[(4-Methylphenyl)Sulfonyl]-1H-Indol-3-Yl)Methylene)Malononitrile is a specialized organic compound belonging to the class of indole-based sulfonamides functionalized with a malononitrile group. This molecular architecture makes it a valuable advanced intermediate and key building block in sophisticated chemical synthesis. It is primarily sought after by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the indole-sulfonamide scaffold is active.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, leveraging its unique heterocyclic structure.
• Organic Electronic Materials: Acts as a building block for creating organic semiconductors, light-emitting diodes (OLEDs), and non-linear optical (NLO) materials due to the electron-accepting malononitrile moiety.
• Dye and Pigment Synthesis: Employed in the production of specialized dyes and pigments, where its conjugated system can be tuned for specific light absorption properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and for exploring new chemical spaces in material science.

Basic Information

Item	Detail
Product Name	2-((1-[(4-Methylphenyl)Sulfonyl]-1H-Indol-3-Yl)Methylene)Malononitrile
CAS No.	477848-99-0
Molecular Formula	C21H15N3O2S
Molecular Weight	373.43 g/mol
Synonyms	2-[(1-(4-Methylphenyl)sulfonyl-1H-indol-3-yl)methylene]propanedinitrile; 2-((1-(p-Tolylsulfonyl)-1H-indol-3-yl)methylene)malononitrile; 2-[(1-Tosyl-1H-indol-3-yl)methylene]malononitrile; (E)-2-((1-Tosyl-1H-indol-3-yl)methylene)malononitrile; 1-Tosyl-3-[(dicyanomethylene)methyl]indole; 3-[(Dicyanomethylene)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indole; TosMIC Indole Malononitrile Adduct; 477848-99-0
EINECS	Contact for details

Quality Control

Our production of 2-((1-[(4-Methylphenyl)Sulfonyl]-1H-Indol-3-Yl)Methylene)Malononitrile adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We operate under a cGMP-compliant quality management system to guarantee batch-to-batch consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.