Description

(E)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-3-(2-Thienyl)-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate featuring a unique chalcone-thiazole hybrid structure. This compound matters for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, contract research organizations (CROs), and academic research laboratories need this precise chemical entity to develop new therapeutic agents targeting a range of diseases.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those with anti-inflammatory, antimicrobial, or anticancer potential.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable chalcone-thiazole scaffold.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds for agrochemical and material science applications.
• Biochemical Probe Development: Utilized in the design and development of molecular probes for studying biological pathways and enzyme interactions.
• Academic & Industrial R&D: A valuable reagent for research institutions and companies focused on discovering new active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(E)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-3-(2-Thienyl)-2-Propen-1-One
CAS No.	477847-69-1
Molecular Formula	C₁₇H₁₃NOS₂
Molecular Weight	311.42 g/mol
Synonyms	(E)-1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)-3-(thiophen-2-yl)prop-2-en-1-one; 2-Propen-1-one, 1-(4-methyl-2-phenyl-5-thiazolyl)-3-(2-thienyl)-, (E)-; (E)-3-(Thiophen-2-yl)-1-(4-methyl-2-phenylthiazol-5-yl)prop-2-en-1-one; Chalcone-thiazole derivative; Thienyl chalcone thiazole; 477847-69-1
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-3-(2-Thienyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.