Description

Methyl 5-[(4-Chlorobenzoyl)Amino]-1-Benzothiophene-2-Carboxylate is a high-purity, synthetic organic compound primarily utilized as a key advanced intermediate in pharmaceutical research and development. Its value lies in its specific molecular architecture, which serves as a critical building block for constructing novel therapeutic agents, particularly in medicinal chemistry programs. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for synthesis and scale-up.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting specific biological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents and herbicides.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for various high-value industrial applications.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory chemical synthesis.

Basic Information

Product Name	Methyl 5-[(4-Chlorobenzoyl)Amino]-1-Benzothiophene-2-Carboxylate
CAS No.	477847-49-7
Molecular Formula	C17H12ClNO3S
Molecular Weight	345.80 g/mol
Synonyms	Methyl 5-[(4-chlorobenzoyl)amino]-1-benzothiophene-2-carboxylate; 5-[(4-Chlorobenzoyl)amino]-1-benzothiophene-2-carboxylic acid methyl ester; 1-Benzothiophene-2-carboxylic acid, 5-[(4-chlorobenzoyl)amino]-, methyl ester; Methyl 5-[(p-chlorobenzoyl)amino]benzo[b]thiophene-2-carboxylate; 477847-49-7; Methyl 5-(4-chlorobenzamido)benzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-[(4-Chlorobenzoyl)Amino]-1-Benzothiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP (current Good Manufacturing Practice) standards ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.