Description

2-Thiophenesulfonamide, n-(1,1-Dimethylethyl)-3-[4-(1H-Imidazol-1-Ylmethyl)Phenyl]-5-(2-Methylpropyl)- is a high-purity, complex heterocyclic sulfonamide derivative designed for advanced research and development. This compound is valued for its unique molecular architecture, which combines thiophene, imidazole, and phenyl moieties, making it a versatile intermediate for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, including the development of enzyme inhibitors and targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and high-throughput screening for identifying new bioactive compounds.
• Enzyme Inhibitor Development: Serves as a core scaffold for designing and optimizing inhibitors for specific enzymatic targets.
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and fine chemical manufacturers specializing in bespoke organic molecules.

Basic Information

Product Name	2-Thiophenesulfonamide, n-(1,1-Dimethylethyl)-3-[4-(1H-Imidazol-1-Ylmethyl)Phenyl]-5-(2-Methylpropyl)-
CAS No.	477775-35-2
Molecular Formula	C22H29N3O2S2
Molecular Weight	431.61 g/mol
Synonyms	tert-Butyl 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-isobutylthiophene-2-sulfonamide; 5-Isobutyl-3-[4-(imidazol-1-ylmethyl)phenyl]thiophene-2-sulfonamide tert-butyl derivative; N-tert-Butyl-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophene-2-sulfonamide; 477775-35-2; Thiophene-2-sulfonamide, N-(1,1-dimethylethyl)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)-; CAS 477775-35-2
EINECS	Contact for details

Quality Control

Our 2-Thiophenesulfonamide derivative is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.