Description

1-(3-Chlorophenyl)-5-(4-Chlorophenyl)-1H-Pyrazole-3-Carboxylic Acid is a high-purity, functionalized pyrazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting inflammation, metabolic disorders, or central nervous system (CNS) diseases.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, or insecticides with improved efficacy and environmental profiles.
• Material Science: Acts as a monomer or functional additive in the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in biochemical assays and drug discovery platforms to study protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	1-(3-Chlorophenyl)-5-(4-Chlorophenyl)-1H-Pyrazole-3-Carboxylic Acid
CAS No.	477711-99-2
Molecular Formula	C16H10Cl2N2O2
Molecular Weight	333.17 g/mol
Synonyms	3-(3,4'-Dichlorobiphenyl-4-yl)-1H-pyrazole-5-carboxylic Acid; 1-(3-Chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carboxylic acid; 5-(4-Chlorophenyl)-1-(3-chlorophenyl)-1H-pyrazole-3-carboxylic Acid; 1H-Pyrazole-3-carboxylic acid, 1-(3-chlorophenyl)-5-(4-chlorophenyl)-; Biphenyl-based pyrazole carboxylic acid; Dichlorophenyl pyrazole carboxylic acid; Pyrazole-3-carboxylic acid derivative CAS 477711-99-2
EINECS	Contact for details

Quality Control

Our production of 1-(3-Chlorophenyl)-5-(4-Chlorophenyl)-1H-Pyrazole-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.