Description

Acetamide, n-(1,2,3,4-Tetrahydro-1-Isoquinolinyl)- is a specialized organic compound belonging to the class of substituted acetamides and tetrahydroisoquinoline derivatives. This high-purity chemical building block is critical for advanced research and development in pharmaceutical chemistry. It serves as a key synthetic intermediate for medicinal chemists and process development scientists working in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used in the design and development of new drug candidates, especially those exploring the tetrahydroisoquinoline pharmacophore.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds and probes to study biological pathways and enzyme functions.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses to introduce specific functional groups and chiral centers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	Acetamide, n-(1,2,3,4-Tetrahydro-1-Isoquinolinyl)-
CAS No.	477532-06-2
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	N-(1,2,3,4-Tetrahydroisoquinolin-1-yl)acetamide; 1-Acetamido-1,2,3,4-tetrahydroisoquinoline; N-(1,2,3,4-Tetrahydro-1-isoquinolinyl)acetamide; Acetamide, N-(1,2,3,4-tetrahydro-1-isoquinolinyl)-; 1-(Acetylamino)-1,2,3,4-tetrahydroisoquinoline; Tetrahydroisoquinoline-1-acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, n-(1,2,3,4-Tetrahydro-1-Isoquinolinyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.