Description

2,4-Thiazolidinedione, 5-[(3-Methylphenyl)Amino]- (9Ci) is a specialized organic compound belonging to the thiazolidinedione class, a group of molecules known for their significant biological activity. This compound serves as a valuable pharmaceutical intermediate and research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D organizations, contract research organizations (CROs), and academic research institutions focused on metabolic and endocrine disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting PPAR (Peroxisome Proliferator-Activated Receptor) pathways.
• Research & Development: Used as a reference standard and active moiety in preclinical studies for metabolic diseases such as type 2 diabetes.
• Chemical Biology: Serves as a probe or ligand in biochemical assays to study receptor-ligand interactions and signal transduction mechanisms.
• Academic Research: Employed in university and institutional labs for investigating the structure-activity relationships (SAR) of thiazolidinedione derivatives.
• Process Chemistry: Used in scale-up and optimization studies for the development of efficient synthetic routes to related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2,4-Thiazolidinedione, 5-[(3-Methylphenyl)Amino]- (9Ci)
CAS No.	477275-66-4
Molecular Formula	C10H10N2O2S
Molecular Weight	222.26 g/mol
Synonyms	5-[(3-Methylphenyl)amino]-2,4-thiazolidinedione; 5-(m-Toluidino)-2,4-thiazolidinedione; 5-(3-Methylanilino)thiazolidine-2,4-dione; TZD derivative; m-Tolyl-thiazolidinedione; PPAR modulator intermediate; CAS 477275-66-4
EINECS	Contact for details

Quality Control

Our 2,4-Thiazolidinedione derivative is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.