Description

Bicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, 5,6-Dihydroxy-, (1R,2S,3R,4S,5R,6R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its rigid, polyfunctional structure, which serves as a sophisticated precursor for complex molecules in pharmaceutical and fine chemical research. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), asymmetric catalysts, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Synthesis: Used to construct complex, enantiopure ligands for transition metal catalysis, enabling highly selective chemical transformations.
• Advanced Material Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways due to its defined stereochemistry and functional groups.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including new cycloaddition and functionalization reactions.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, 5,6-Dihydroxy-, (1R,2S,3R,4S,5R,6R)-Rel- (9Ci)
CAS No.	477248-99-0
Molecular Formula	C9H12O6
Molecular Weight	216.19 g/mol
Synonyms	(1R,2S,3R,4S,5R,6R)-5,6-Dihydroxybicyclo[2.2.1]heptane-2,3-dicarboxylic acid; rel-(1R,2S,3R,4S,5R,6R)-5,6-Dihydroxybicyclo[2.2.1]heptane-2,3-dicarboxylic acid; 5,6-Dihydroxy-2,3-norbornanedicarboxylic acid (stereospecific); Bicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 5,6-dihydroxy-, (1R,2S,3R,4S,5R,6R)-rel-; Norborneol dicarboxylic acid derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to guarantee high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.