Description

2-Acetylbutyrolactone-3,3,4,4-D4 is a deuterated derivative of 2-acetylbutyrolactone, a valuable chemical intermediate. This compound is specifically designed for applications requiring stable isotope labeling, offering enhanced analytical precision and metabolic stability in research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for synthesis, process development, and analytical method validation.

Application

• Deuterated Standard for Analytical Chemistry: Used as an internal standard in mass spectrometry (MS), nuclear magnetic resonance (NMR), and liquid chromatography-mass spectrometry (LC-MS) for accurate quantification and method validation.
• Pharmaceutical Research & Development: Serves as a key labeled intermediate in the synthesis of deuterated drug candidates for pharmacokinetic, metabolic, and tracer studies.
• Agrochemical Research: Employed in the development of labeled pesticides and herbicides to study environmental fate, degradation pathways, and residue analysis.
• Metabolic Pathway Tracing: Facilitates the study of biochemical pathways and mechanisms in biological systems due to its isotopic label.
• Material Science: Potential use in the synthesis of specialty polymers and advanced organic electronic materials where isotopic purity can influence physical properties.

Basic Information

Product Name	2-Acetylbutyrolactone-3,3,4,4-D4
CAS No.	476646-93-2
Molecular Formula	C₆H₄D₄O₃
Molecular Weight	~130.15 g/mol
Synonyms	2-Acetyl-γ-butyrolactone-d4; 3,3,4,4-Tetradeutero-2-acetylbutyrolactone; 2-Acetyl-4-butanolide-d4; 2-Acetyldihydro-2(3H)-furanone-d4; α-Acetyl-γ-butyrolactone-d4; Deuterated 2-Acetylbutyrolactone; 2-Acetyl-γ-butyrolactone (3,3,4,4-d4); 2-Acetyl-4-hydroxybutanoic acid lactone-d4
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality control protocols to ensure high isotopic and chemical purity. Each batch is characterized using advanced analytical techniques including NMR, MS, and HPLC. Certificates of Analysis (COA) are provided, detailing isotopic enrichment (D-atom %), chemical purity, and relevant spectroscopic data to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (D-atom %)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.