Description

7-Fluoro-4-Methoxy-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its distinct fluorinated benzothiophene core structure. This compound is critical for medicinal chemistry research and development, offering a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated heterocyclic motifs into their molecular targets.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to the favorable properties imparted by the fluorine atom and methoxy group.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides that require fluorinated heterocyclic components for enhanced activity and environmental stability.
• Material Science Precursor: Potential use in the development of organic electronic materials, such as semiconductors or light-emitting materials, where the benzothiophene scaffold is valuable.
• Chemical Biology Probe: Can be utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	7-Fluoro-4-Methoxy-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	476199-02-7
Molecular Formula	C11H9FO3S
Molecular Weight	240.25 g/mol
Synonyms	Methyl 7-Fluoro-4-methoxybenzo[b]thiophene-2-carboxylate; 7-Fluoro-4-methoxy-1-benzothiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-7-fluoro-4-methoxybenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 7-fluoro-4-methoxy-, methyl ester; 476199-02-7
EINECS	Contact for details

Quality Control

Our 7-Fluoro-4-Methoxy-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.