Description

1-Boc-2-Dimethylsilanyl-5-Methyl-Indole is a sophisticated, high-purity protected indole derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality intermediates for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to introduce functionalized indole motifs.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides that utilize indole-based structures.
• Material Science: Potential monomer or precursor for creating specialized polymers and advanced organic materials.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	1-Boc-2-Dimethylsilanyl-5-Methyl-Indole
CAS No.	475102-17-1
Molecular Formula	C₁₆H₂₃NO₂Si
Molecular Weight	289.45 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-2-(dimethylsilyl)-5-methyl-1H-indole; 2-(Dimethylsilyl)-5-methyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-Boc-2-(dimethylsilyl)-5-methylindole; tert-Butyl 2-(dimethylsilyl)-5-methyl-1H-indole-1-carboxylate; 5-Methyl-1-Boc-2-(dimethylsilyl)indole; 1-Boc-2-(dimethylhydrosilyl)-5-methylindole; 1-Boc-2-dimethylsilyl-5-methylindole; 1-Boc-2-(dimethylsilyl)-5-methyl-1H-indole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (typically by HPLC or GC), residual solvents, and other critical parameters are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.