Description

1-Boc-5-Cyanoindole is a high-purity, protected indole derivative serving as a critical building block in modern organic synthesis. This compound is essential for the efficient construction of complex heterocyclic scaffolds, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile reactive sites.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides with specific biological activity.
• Functional Material Development: Employed in the creation of organic electronic materials, dyes, and photoactive compounds.
• Peptidomimetics & Bioconjugation: The Boc-protected amine and cyano group facilitate its use in designing peptide analogs and bioconjugation linkers.
• Academic & Contract Research: A valuable reagent for methodological development and custom synthesis in academic and CRO laboratories.

Basic Information

Product Name	1-Boc-5-Cyanoindole
CAS No.	475102-10-4
Molecular Formula	C₁₄H₁₄N₂O₂
Molecular Weight	242.27 g/mol
Synonyms	5-Cyano-1H-indole-1-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 5-cyano-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-cyanoindole; N-Boc-5-cyanoindole; Boc-5-cyanoindole; 5-Cyanoindole-1-N-Boc; 1-Boc-5-cyano-1H-indole
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Cyanoindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.