Description

3-Amino-5-(3-Nitro-Phenyl)-Thiophene-2-Carboxylic Acid Methyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and functional materials, particularly those targeting specific biological pathways. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating new active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its unique thiophene and nitro-phenyl structure.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye & Pigment Synthesis: Employed in the creation of specialized dyes and pigments due to its conjugated system and functional groups.
• Chemical Biology Probes: Utilized in the design of molecular probes and sensors for biochemical research and diagnostics.
• Academic & Contract Research: A valuable reagent for method development and exploratory chemistry in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	3-Amino-5-(3-Nitro-Phenyl)-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	474843-42-0
Molecular Formula	C12H10N2O4S
Molecular Weight	278.29 g/mol
Synonyms	Methyl 3-amino-5-(3-nitrophenyl)thiophene-2-carboxylate; 3-Amino-5-(3-nitrophenyl)-2-thiophenecarboxylic acid methyl ester; 3-Nitrophenylthiophene methyl ester; 474843-42-0; Thiophene-2-carboxylic acid, 3-amino-5-(3-nitrophenyl)-, methyl ester; Methyl 3-amino-5-(m-nitrophenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(3-Nitro-Phenyl)-Thiophene-2-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.