Description

3-Amino-5-(4-benzyloxyphenyl)thiophene-2-carboxylic acid methyl ester is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of novel heterocyclic compounds, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the thiophene core for bioactive molecule design.
• Material Science: Acts as a monomer or functional unit in the research of conductive polymers and organic semiconductors due to the electron-rich thiophene moiety.
• Dye & Pigment Synthesis: Employed in the creation of advanced organic dyes and pigments where the amino and ester functionalities allow for further chemical modification.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for biological imaging and diagnostic applications.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-Amino-5-(4-benzyloxyphenyl)thiophene-2-carboxylic acid methyl ester
CAS No.	474843-40-8
Molecular Formula	C19H17NO3S
Molecular Weight	339.41 g/mol
Synonyms	Methyl 3-amino-5-(4-(benzyloxy)phenyl)thiophene-2-carboxylate; 3-Amino-5-(4-benzyloxyphenyl)-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-[4-(phenylmethoxy)phenyl]-, methyl ester; Methyl 3-amino-5-[4-(benzyloxy)phenyl]thiophene-2-carboxylate; 474843-40-8; AKOS BRN 0972
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(4-benzyloxyphenyl)thiophene-2-carboxylic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.