Description

1,2-Dibromo-4,5-diethoxy-3-fluorobenzene is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique substitution pattern, which makes it a versatile intermediate in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine and bromine atoms for bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen functionalities.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination to introduce complex aryl groups.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening for drug discovery programs.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of fluorine substitution on aromatic systems.

Basic Information

Product Name	1,2-Dibromo-4,5-Diethoxy-3-Fluorobenzene
CAS No.	474554-34-2
Molecular Formula	C10H11Br2FO2
Molecular Weight	366.00 g/mol
Synonyms	3-Fluoro-4,5-diethoxy-1,2-dibromobenzene; 4,5-Diethoxy-1,2-dibromo-3-fluorobenzene; Benzene, 1,2-dibromo-4,5-diethoxy-3-fluoro-; 1,2-Dibromo-4,5-diethoxy-3-fluorobenzene; 3-Fluoro-1,2-dibromo-4,5-diethoxybenzene
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-4,5-diethoxy-3-fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.