Description

Phospholane, 1-Hydroxy-2,5-Diphenyl-, 1-Oxide, (2S,5S)- is a high-purity, chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a versatile ligand and building block for the development of asymmetric catalysts and novel pharmaceutical intermediates. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure components for complex synthesis.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal catalysts in enantioselective hydrogenation, hydroformylation, and other C-C bond-forming reactions.
• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science Research: A precursor for creating chiral polymers or functional materials with specific optical or catalytic properties.
• Academic & Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis studies.

Basic Information

Product Name	Phospholane, 1-Hydroxy-2,5-Diphenyl-, 1-Oxide, (2S,5S)-
CAS No.	474049-73-5
Molecular Formula	C17H17O2P
Molecular Weight	284.29 g/mol
Synonyms	(2S,5S)-1-Hydroxy-2,5-diphenylphospholane 1-oxide; (2S,5S)-2,5-Diphenyl-1-hydroxyphospholane 1-oxide; (S,S)-1-Hydroxy-2,5-diphenylphospholane P-oxide; (S,S)-HPOP; (S,S)-2,5-Diphenylphospholane-1-ol 1-oxide; Chiral HPOP ligand; (S,S)-1-Hydroxy-2,5-diphenylphospholane 1-oxide
EINECS	Contact for details

Quality Control

Our (2S,5S)-1-Hydroxy-2,5-diphenylphospholane 1-oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and IR for structural confirmation, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.