Description

1H-2-Benzopyran-1-One, 4-(1,2-Dihydroxyethyl)-4A,8A-Dihydro-8-Hydroxy- (9Ci) is a specialized benzopyran derivative with a unique polyhydroxylated structure, making it a valuable chiral intermediate and building block in advanced organic synthesis. This compound is critical for research and development in fine chemical and pharmaceutical sectors where precise molecular architecture is required. It is primarily sought after by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), complex natural product analogs, and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic pathways.
• Fine Chemical Synthesis: Used as a versatile building block for constructing benzopyran and chromane scaffolds prevalent in agrochemicals and functional materials.
• Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Asymmetric Catalysis: Acts as a precursor or ligand in catalytic systems due to its multiple stereocenters and hydroxyl functional groups.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	1H-2-Benzopyran-1-One, 4-(1,2-Dihydroxyethyl)-4A,8A-Dihydro-8-Hydroxy- (9Ci)
CAS No.	473929-90-7
Molecular Formula	C11H12O5
Molecular Weight	224.21 g/mol
Synonyms	4-(1,2-Dihydroxyethyl)-4a,8a-dihydro-8-hydroxy-1H-2-benzopyran-1-one; 4-(1,2-Dihydroxyethyl)-4a,8a-dihydro-8-hydroxyisochroman-1-one; 8-Hydroxy-4-(1,2-dihydroxyethyl)-4a,8a-dihydro-1H-isochromen-1-one; 473929-90-7; Polyhydroxyisochromanone derivative; Dihydroxyethyl dihydrohydroxybenzopyranone
EINECS	Contact for details

Quality Control

Our 1H-2-Benzopyran-1-One, 4-(1,2-Dihydroxyethyl)-4A,8A-Dihydro-8-Hydroxy- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications are designed to meet the stringent needs of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.