Description

Bicyclo[3.1.0]Hexane-2-Acetic Acid, 2-(Aminomethyl)-6,6-Dimethyl-, (1R,2S,5S)- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, three-dimensional scaffold is engineered to impart specific conformational constraints, making it invaluable for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, receptor modulators, and other small-molecule therapeutics.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and binding affinity.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides with improved selectivity.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science & Specialty Polymers: Can be incorporated into polymers to create materials with unique structural and functional properties.
• Academic & Contract Research: Utilized in fundamental organic chemistry research and by CROs (Contract Research Organizations) for client-specific synthetic projects.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-2-Acetic Acid, 2-(Aminomethyl)-6,6-Dimethyl-, (1R,2S,5S)- (9Ci)
CAS No.	473829-50-4
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	(1R,2S,5S)-2-(Aminomethyl)-6,6-dimethylbicyclo[3.1.0]hexane-2-acetic acid; (1R,2S,5S)-2-(Aminomethyl)-6,6-dimethylbicyclo[3.1.0]hexan-2-ylacetic acid; Rel-(1R,2S,5S)-Bicyclo[3.1.0]hexane-2-acetic acid, 2-(aminomethyl)-6,6-dimethyl-; Bicyclo[3.1.0]hexane-2-acetic acid, 2-(aminomethyl)-6,6-dimethyl-, (1R,2S,5S)-; 473829-50-4; (1R,2S,5S)-2-(Aminomethyl)-6,6-dimethyl-2-bicyclo[3.1.0]hexylacetic acid
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[3.1.0]Hexane-2-Acetic Acid, 2-(Aminomethyl)-6,6-Dimethyl-, (1R,2S,5S)- (9Ci) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.