Description

4-Methylphenyl 3-o-Benzyl-4,6- o-Benzylidene-1-Thio-β-D-Gluco- Pyranoside is a sophisticated, high-purity carbohydrate derivative and thioglycoside building block. This compound is critical for synthetic chemists as a key chiral intermediate in the synthesis of complex oligosaccharides, glycoconjugates, and biologically active molecules. It is primarily utilized in advanced pharmaceutical research, process development, and the production of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel glycosidase inhibitors, antiviral agents, and other therapeutic glycoconjugates.
• Glycochemistry Research: Serves as a protected thioglycoside donor in oligosaccharide assembly and solid-phase synthesis for studying carbohydrate-protein interactions.
• Process Development: Used in scaling up routes to complex carbohydrate-based Active Pharmaceutical Ingredients (APIs) and fine chemicals.
• Bioconjugation: Acts as a building block for creating labeled probes, vaccine components, and targeted drug delivery systems.
• Academic & Industrial R&D: Essential for exploring new synthetic methodologies in glycoscience and developing carbohydrate-based materials.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	4-Methylphenyl 3-o-Benzyl-4,6- o-Benzylidene-1-Thio-β-D-Gluco- Pyranoside
CAS No.	473711-83-0
Molecular Formula	C27H28O5S
Molecular Weight	464.58 g/mol
Synonyms	4-Methylphenyl 1-thio-β-D-glucopyranoside, 3-O-benzyl-4,6-O-benzylidene; 1-Thio-β-D-glucopyranoside, 4-methylphenyl 3-O-benzyl-4,6-O-benzylidene; p-Tolyl 3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside; Thioglycoside donor S1; Benzylidene-protected thioglucoside; 3-O-Benzyl-4,6-O-benzylidene-1-S-(4-methylphenyl)-1-thio-β-D-glucopyranose
EINECS	Contact for details

Quality Control

Every batch of 4-Methylphenyl 3-o-Benzyl-4,6- o-Benzylidene-1-Thio-β-D-Gluco- Pyranoside is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.