Description

Ethyl 4-(2-Chloro-5-Thienyl)-4-Oxobutyrate is a high-purity organic building block characterized by its functionalized thiophene and ester groups. This compound is of significant value in advanced organic synthesis, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiophene moiety.
• Material Science Research: Serves as a monomer or building block for developing advanced polymers and organic electronic materials, such as conductive polymers or organic semiconductors.
• Chemical Research & Development: Employed in method development and as a standard in analytical chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing specialized fine chemicals for client-specific projects.

Basic Information

Product Name	Ethyl 4-(2-Chloro-5-Thienyl)-4-Oxobutyrate
CAS No.	473694-31-4
Molecular Formula	C10H11ClO3S
Molecular Weight	246.71 g/mol
Synonyms	Ethyl 4-(2-chlorothiophen-5-yl)-4-oxobutanoate; 4-(2-Chloro-5-thienyl)-4-oxobutyric Acid Ethyl Ester; 2-Chloro-5-(3-ethoxy-3-oxopropanoyl)thiophene; Butanoic acid, 4-(2-chloro-5-thienyl)-4-oxo-, ethyl ester; Ethyl 4-oxo-4-(2-chlorothiophen-5-yl)butyrate; 473694-31-4; AKOS BRN 0972
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-(2-Chloro-5-Thienyl)-4-Oxobutyrate is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.