Description

5-Chloro-4-Fluoro-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the creation of new drug candidates, agrochemicals, and other fine chemicals where the indole scaffold is essential.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas, leveraging the bioactive indole core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where halogenated indoles can exhibit potent biological activity.
• Material Science: Serves as a monomer or building block for creating specialized polymers or organic electronic materials with unique properties.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical research due to its functionalizable carboxylic ester group.
• Academic & R&D: Utilized in university and industrial laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	5-Chloro-4-Fluoro-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	473257-61-3
Molecular Formula	C11H9ClFNO2
Molecular Weight	241.65 g/mol
Synonyms	Ethyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; 5-Chloro-4-fluoroindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 5-chloro-4-fluoro-, ethyl ester; 473257-61-3; Ethyl 5-chloro-4-fluoroindole-2-carboxylate; 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid ethyl ester; 2-Carbethoxy-5-chloro-4-fluoroindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Fluoro-1H-Indole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.