Description

Carbamic Acid, 1H-Indol-5-Yl-, Methyl Ester (9Ci) is a specialized indole-derived carbamate ester, a high-value chemical intermediate with significant utility in advanced organic synthesis. Its core value proposition lies in its role as a versatile building block for constructing complex nitrogen-containing heterocycles, which are pivotal in modern pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the privileged indole scaffold.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the carbamate functional group can impart specific biological activity.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of complex molecular libraries for high-throughput screening.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling and modifying biomolecules, leveraging its reactive ester group.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	Carbamic Acid, 1H-Indol-5-Yl-, Methyl Ester (9Ci)
CAS No.	470454-96-7
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	Methyl 5-indolylcarbamate; 1H-Indol-5-yl-carbamic acid methyl ester; 5-Indolylcarbamic Acid Methyl Ester; Methyl (1H-indol-5-yl)carbamate; Carbamic acid, (1H-indol-5-yl)-, methyl ester; (1H-Indol-5-yl)carbamic acid methyl ester; 5-(Methoxycarbonylamino)indole
EINECS	Contact for details

Quality Control

Our Carbamic Acid, 1H-Indol-5-Yl-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.