Description

3-Chloro-N'-[(2E)-3-(Furan-2-Yl)Prop-2-Enoyl]-1-Benzothiophene-2-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its potential as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating new chemical entities targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting kinase inhibition or other enzymatic pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological processes and protein function due to its specific molecular architecture.
• Organic Synthesis: Acts as a versatile intermediate for constructing complex heterocyclic systems containing benzothiophene and furan motifs.
• Agrochemical Research: Potential application in the research and development of new active ingredients for crop protection products.

Basic Information

Product Name	3-Chloro-N'-[(2E)-3-(Furan-2-Yl)Prop-2-Enoyl]-1-Benzothiophene-2-Carbohydrazide
CAS No.	468759-29-7
Molecular Formula	C₁₆H₁₁ClN₂O₃S
Molecular Weight	346.79 g/mol
Synonyms	3-Chloro-1-benzothiophene-2-carboxylic acid [(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]hydrazide; 3-Chloro-N'-[(E)-3-(furan-2-yl)acryloyl]benzo[b]thiophene-2-carbohydrazide; 3-Chloro-N'-(3-(furan-2-yl)acryloyl)benzo[b]thiophene-2-carbohydrazide; (E)-3-Chloro-N'-(3-(furan-2-yl)acryloyl)benzo[b]thiophene-2-carbohydrazide; CAS 468759-29-7; 3-Chloro-1-benzothiophene-2-carbohydrazide derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 3-Chloro-N'-[(2E)-3-(Furan-2-Yl)Prop-2-Enoyl]-1-Benzothiophene-2-Carbohydrazide is characterized and controlled using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical quality attributes are available upon request. Our quality system is designed to support cGMP-compliant development and manufacturing activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.