Description

Bicyclo[2.2.1]Heptane-2-Carboxamide, n-(2,4-Difluorophenyl)- (9Ci) is a high-purity, specialized organic compound featuring a norbornane (bicyclo[2.2.1]heptane) core functionalized with a difluorophenyl carboxamide group. This compound matters as a critical pharmaceutical intermediate and advanced building block for medicinal chemistry research, enabling the synthesis of novel active molecules. It is primarily needed by R&D teams and process chemists in the pharmaceutical, agrochemical, and advanced material sectors for developing new drugs and functional chemicals.

Application

This specialized carboxamide serves as a versatile scaffold in advanced chemical synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key building block for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its rigid norbornane structure and fluorinated aromatic moiety.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, or pesticides with enhanced biological activity and stability.
• Ligand and Catalyst Development: The amide and fluorine groups make it a candidate for constructing chiral ligands or organocatalysts used in asymmetric synthesis.
• Advanced Material Precursor: Potential use in synthesizing monomers for high-performance polymers or liquid crystals, leveraging its thermally stable and rigid bicyclic framework.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxamide, n-(2,4-Difluorophenyl)- (9Ci)
CAS No.	468744-12-9
Molecular Formula	C14H15F2NO
Molecular Weight	251.27 g/mol
Synonyms	N-(2,4-Difluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide; 2-Norbornanecarboxamide, N-(2,4-difluorophenyl)-; N-(2,4-Difluorophenyl)-2-norbornanecarboxamide; Bicyclo[2.2.1]heptane-2-carboxylic acid (2,4-difluoroanilide); endo-N-(2,4-Difluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide (potential isomer); exo-N-(2,4-Difluorophenyl)bicyclo[2.2.1]heptane-2-carboxamide (potential isomer)
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Carboxamide, n-(2,4-Difluorophenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Isomer Ratio (endo/exo)	Specified per batch (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.