Description

3-(2-Carboxy-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional nature, featuring both a carboxylic acid and a tert-butyl ester-protected indole nitrogen, enabling precise and sequential chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Building block for developing new generation herbicides and plant growth regulators with specific biological activity.
• Peptide Mimetics: Used to incorporate indole scaffolds into peptide chains, creating novel structures for drug discovery.
• Material Science: Intermediate for synthesizing specialty polymers and organic electronic materials requiring specific indole functionalities.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds and probes used in biochemical assays and diagnostic research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthetic routes on a commercial scale.

Basic Information

Product Name	3-(2-Carboxy-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	468721-38-2
Molecular Formula	C₁₆H₁₉NO₄
Molecular Weight	289.33 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-(2-carboxyethyl)indole; 1-Boc-3-(2-carboxyethyl)indole; tert-Butyl 3-(2-carboxyethyl)-1H-indole-1-carboxylate; 3-(2-Carboxyethyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-Boc-3-indolepropionic acid; 3-(2-Carboxyethyl)indole-1-carboxylic acid tert-butyl ester; BOC-Indole-3-propionic Acid; N-Boc-3-indolepropionic acid
EINECS	Contact for details

Quality Control

Our 3-(2-Carboxy-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.