Description

3-Formyl-1-Tosyl-1H-Indole-5-Carbonitrile is a high-value, multi-functional indole derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring both formyl and tosyl protecting groups alongside a nitrile moiety, makes it an exceptionally versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, dyes, and photoresponsive polymers.
• Academic & R&D: Employed in methodological studies for novel cross-coupling, cyclization, and functional group transformation reactions.
• Chemical Biology: Utilized as a probe or linker in the synthesis of bioconjugates and molecular tools for studying biological processes.

Basic Information

Product Name	3-Formyl-1-Tosyl-1H-Indole-5-Carbonitrile
CAS No.	468717-73-9
Molecular Formula	C17H12N2O3S
Molecular Weight	324.35 g/mol
Synonyms	5-Cyano-1-tosyl-1H-indole-3-carboxaldehyde; 1-(4-Methylphenyl)sulfonyl-1H-indole-5-carbonitrile-3-carboxaldehyde; 3-Formyl-1-(p-toluenesulfonyl)-1H-indole-5-carbonitrile; 1-Tosyl-3-formyl-1H-indole-5-carbonitrile; 1H-Indole-5-carbonitrile, 3-formyl-1-[(4-methylphenyl)sulfonyl]-; 5-Cyano-3-formyl-1-tosylindole; 3-Carbaldehyde-1-tosyl-1H-indole-5-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Formyl-1-Tosyl-1H-Indole-5-Carbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, prolonged exposure to light and air should be avoided. For long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.