Description

6-Oxa-1-Azabicyclo[3.1.0]Hexane-2-Carboxylicacid,Ethylester,(2S,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic heterocyclic compound, serving as a critical chiral building block in advanced organic synthesis. Its unique fused oxazolidine-cyclopropane structure makes it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those targeting enzymatic pathways.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, including antibiotics, enzyme inhibitors, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for creating novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Chemical Biology & Proteomics: Used in the design and synthesis of activity-based probes (ABPs) and molecular tools for studying biological mechanisms.
• Asymmetric Catalysis Research: Serves as a precursor or ligand framework in the development of new chiral catalysts for stereoselective transformations.
• Material Science Research: Potential monomer or precursor for synthesizing specialized polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and medicinal chemistry programs at research institutions and CROs.

Basic Information

Product Name	6-Oxa-1-Azabicyclo[3.1.0]Hexane-2-Carboxylicacid,Ethylester,(2S,5R)-(9Ci)
CAS No.	468096-97-1
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	(2S,5R)-Ethyl 6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate; (2S,5R)-Ethyl 6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylic acid ester; Ethyl (1S,5R,6S)-6-oxa-1-azabicyclo[3.1.0]hexane-1-carboxylate; 6-Oxa-1-azabicyclo[3.1.0]hexane-2-carboxylic acid, ethyl ester, (1S,5R,6S)-rel-; Bicyclic oxazolidine-cyclopropane ethyl ester; (2S,5R)-6-Oxa-1-azabicyclo[3.1.0]hexane-2-carboxylic acid ethyl ester; Azabicyclohexane carboxylate derivative.
EINECS	Contact for details

Quality Control

Our production of 6-Oxa-1-Azabicyclo[3.1.0]Hexane-2-Carboxylicacid,Ethylester,(2S,5R)-(9Ci) adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and stereochemical purity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maximize stability and shelf-life.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (2S,5R)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.