Description

6-(Methylsulfonyl)-1H-Indole is a high-purity, functionalized indole derivative characterized by a methylsulfonyl substituent at the 6-position. This specific molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate (API) and a critical building block in modern organic synthesis. It is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel therapeutic agents, particularly in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Organic Synthesis Building Block: The methylsulfonyl group acts as a versatile handle for further functionalization via cross-coupling reactions, making it essential for creating diverse chemical entities.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	6-(Methylsulfonyl)-1H-Indole
CAS No.	467461-40-1
Molecular Formula	C9H9NO2S
Molecular Weight	195.24 g/mol
Synonyms	1H-Indole, 6-(methylsulfonyl)-; 6-Methanesulfonyl-1H-indole; 6-(Methylsulfonyl)indole; 6-Methylsulfonylindole; 6-(Methanesulphonyl)indole; 467461-40-1 (CAS); 6-(Methylsulfonyl)indole
EINECS	Contact for details

Quality Control

Our production of 6-(Methylsulfonyl)-1H-Indole adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.