Description

1H-Indole-3-Ethanamine, 6-Fluoro-n-[[3-(2,2,3,3-Tetrafluoropropoxy)Phenyl]Methyl]- is a high-purity, structurally complex fluorinated indole derivative designed for advanced research and development. This compound is of significant interest as a key synthetic intermediate in the creation of novel bioactive molecules, particularly within the pharmaceutical sector. It is primarily targeted at medicinal chemistry and process development teams in pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorinated side chains on biological activity and metabolic stability.
• Agrochemical Development: Acts as a precursor in the research and development of new-generation pesticides and herbicides with enhanced efficacy.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe to study specific enzyme interactions or receptor binding.
• Fine Chemical Synthesis: Utilized in multi-step synthetic routes for producing complex, high-value specialty chemicals.

Basic Information

Product Name	1H-Indole-3-Ethanamine, 6-Fluoro-n-[[3-(2,2,3,3-Tetrafluoropropoxy)Phenyl]Methyl]-
CAS No.	467459-31-0
Molecular Formula	C20H19F5N2O
Molecular Weight	398.37 g/mol
Synonyms	6-Fluoro-N-{[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl}-1H-indole-3-ethanamine; 6-Fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]tryptamine; 2-(6-Fluoro-1H-indol-3-yl)-N-{[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl}ethan-1-amine; Fluorinated Tryptamine Derivative; 467459-31-0; 6-Fluoro-N-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)tryptamine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.