Description

1H-Indole,4,6-Difluoro-5-Methoxy-(9Ci) is a high-purity, fluorinated indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates fluorine and methoxy substituents to modulate electronic properties and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-rich indole core and substituent effects.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1H-Indole,4,6-Difluoro-5-Methoxy-(9Ci)
CAS No.	467452-32-0
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	4,6-Difluoro-5-methoxy-1H-indole; 5-Methoxy-4,6-difluoro-1H-indole; 1H-Indole, 4,6-difluoro-5-methoxy-; 4,6-Difluoro-5-methoxyindole; 467452-32-0; 4,6-Difluoro-5-methoxy-1H-indole (9CI)
EINECS	Contact for details

Quality Control

Our 1H-Indole,4,6-Difluoro-5-Methoxy-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.