Description

2-(5-(Trifluoromethoxy)-1H-Indol-3-Yl)Ethanamine Hydrochloride is a high-purity, synthetically derived indole derivative, specifically a tryptamine hydrochloride salt, valued for its role as a critical pharmaceutical intermediate. Its molecular structure, featuring a trifluoromethoxy substituent, makes it a key building block in medicinal chemistry for the development of novel therapeutic agents. This compound is primarily targeted at research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of bioactive molecules, particularly within central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Tool Compound: Employed in pharmacological research to study receptor interactions and signal transduction pathways related to indoleamine systems.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Acts as a specialized intermediate in multi-step organic syntheses for producing complex, fluorinated organic molecules.

Basic Information

Product Name	2-(5-(Trifluoromethoxy)-1H-Indol-3-Yl)Ethanamine Hydrochloride
CAS No.	467452-24-0
Molecular Formula	C11H12F3N2O • HCl
Molecular Weight	280.68 g/mol (Free base: 244.22 g/mol)
Synonyms	5-(Trifluoromethoxy)tryptamine hydrochloride; 2-(5-Trifluoromethoxy-1H-indol-3-yl)ethanamine HCl; 5-TFMT HCl; α-Ethyl-5-(trifluoromethoxy)indole-3-ethanamine hydrochloride; 3-(2-Aminoethyl)-5-(trifluoromethoxy)indole hydrochloride; 5-Trifluoromethoxytryptamine HCl; 5-CF3O-T HCl
EINECS	Contact for details

Quality Control

Our 2-(5-(Trifluoromethoxy)-1H-Indol-3-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our commitment is to deliver material of consistent high purity and reliable performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.